Functional fluorine-doped tin oxide coating for opto-electrochemical label-free biosensors

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F22%3A43904755" target="_blank" >RIV/60076658:12310/22:43904755 - isvavai.cz</a>

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0925400522007870?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0925400522007870?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.snb.2022.132145" target="_blank" >10.1016/j.snb.2022.132145</a>

Result language

angličtina

Original language name

Functional fluorine-doped tin oxide coating for opto-electrochemical label-free biosensors

Original language description

Sensors operating in multiple domains, such as optical and electrochemical, offer properties making biosensing more effective than those working in a single domain. To combine such domains in one sensing device, materials offering a certain set of properties are required. Fluorine-doped tin oxide (FTO) thin film is discussed in this work as functional optically for guiding lossy modes and simultaneously electrochemically, i.e. as a conductive material for a working electrode. Performance of the FTO-based optical fiber lossy-mode resonance (LMR) sensor in both optical and electrochemical domains is analyzed. Additionally, to enhance applicability of the sensor, its probe-like reflection configuration has been developed. It is found that FTO may be considered as a promising alternative for other thin conductive oxides (TCO), such as indium tin oxide (ITO) that has been often applied up to date in various dual-domain sensing concepts. In the optical domain, the sensitivity of the FTO-LMR sensor to external refractive index (RI) has reached 450 nm/RIU in the RI range of 1.33-1.40 RIU. In the electrochemical domain, in turn, the response for FTO electrode in 1,1 &amp; PRIME;-Ferrocenedimethanol solution has been reached with RedOx current low peak-to-peak separation. In contrast to the ITO-LMR sensors, the FTO-LMR counterparts exhibit a significant influence of applied potential on LMR wavelength shift in a wide potential range. It is shown using streptavidin as a target biomaterial that label-free biosensing applications of the FTO-LMR approach are possible. The dual-domain functionality allows for cross-verification between readouts received in both the domains, as well as enhancement of optical sensitivity when cross-domain interactions are applied.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

Project

<a href="/en/project/GA19-20168S" target="_blank" >GA19-20168S: Nanostructures for LSPR biosensors based on optical fibre</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Sensors and Actuators B: Chemical

ISSN

0925-4005

e-ISSN

0925-4005

Volume of the periodical

367

Issue of the periodical within the volume

SEP 15 2022

Country of publishing house

CH - SWITZERLAND

Number of pages

12

Pages from-to

nestrankovano

UT code for WoS article

000811974000008

EID of the result in the Scopus database

2-s2.0-85131730977