All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

External complexation of BODIPYs by CB[7] improves in-cell fluorescence imaging

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F22%3A43904770" target="_blank" >RIV/60076658:12310/22:43904770 - isvavai.cz</a>

  • Result on the web

    <a href="https://pubs.rsc.org/en/content/articlepdf/2022/ma/d1ma00931a" target="_blank" >https://pubs.rsc.org/en/content/articlepdf/2022/ma/d1ma00931a</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1039/d1ma00931a" target="_blank" >10.1039/d1ma00931a</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    External complexation of BODIPYs by CB[7] improves in-cell fluorescence imaging

  • Original language description

    Organic luminescent compounds with high emission properties play a crucial role in fluorescence labelling and optoelectronic devices. In this work, we prepared three water soluble BODIPY derivatives (B-4, B-5, and B-6) which are weakly fluorescent due to non-radiative relaxation pathways (charge transfer: CT or heavy atom effect). However, CB[7] significantly improves BODIPY fluorescence by similar to 10 fold for B-4, and by similar to 3 fold for B-5. The (TD)DFT analyses suggest that for B-4 and B-5, the CT state is blue-shifted as a result of the external binding of CB[7] near the pyridinium groups. This effect favoured a radiative decay through a locally-excited (LE) pi -&gt;pi* transition state of BODIPYs resulting in a CB[7]-induced emission increase in solution (and in the solid state), without compromising singlet-to-triplet intersystem crossing (ISC). The improved emission of the BODIPY center dot CB[7] complexes was used for the fluorescence imaging of U87 cells illustrating the relevance of this approach. These results suggest that BODIPY center dot CB[7] complexes could be used as theragnostic agents by combining fluorescence imaging and treatment by photodynamic therapy.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database

  • CEP classification

  • OECD FORD branch

    10403 - Physical chemistry

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Materials Advances

  • ISSN

    2633-5409

  • e-ISSN

    2633-5409

  • Volume of the periodical

    3

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    7

  • Pages from-to

    547-553

  • UT code for WoS article

    000721888500001

  • EID of the result in the Scopus database

    2-s2.0-85122886799