Holobiont-holobiont interactions across host-ectoparasite systems
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F25%3A43910342" target="_blank" >RIV/60076658:12310/25:43910342 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/article/10.1186/s13071-025-07026-0?utm_source=getftr&utm_medium=getftr&utm_campaign=getftr_pilot&getft_integrator=clarivate" target="_blank" >https://link.springer.com/article/10.1186/s13071-025-07026-0?utm_source=getftr&utm_medium=getftr&utm_campaign=getftr_pilot&getft_integrator=clarivate</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s13071-025-07026-0" target="_blank" >10.1186/s13071-025-07026-0</a>
Alternative languages
Result language
angličtina
Original language name
Holobiont-holobiont interactions across host-ectoparasite systems
Original language description
Holobionts - hosts together with their resident microorganisms - provide a framework for studying life as a network of interdependent partners. Within host-ectoparasite holobionts, the dialogue between the two microbiomes offers powerful clues to ecological balance, disease dynamics and evolution. Because each holobiont is structurally and functionally compartmentalised, microbes exchanged at the interface can elicit highly local, niche-specific effects that ripple through the system. This review synthesises evidence for microbiota-to-microbiota interactions in four models: Varroa mite-honeybee, tick-vertebrate, bat fly-bat and mosquito-vertebrate pairs. In all cases, microbes move passively during feeding or contact, then colonise, replicate and modulate physiology and immunity, exerting a longer-lasting influence than transient biochemical cues. We further introduce the idea of indirect modulation, whereby abiotic or biotic factors act on a recipient holobiont through the intermediary of transferred microbes, underscoring the adaptive plasticity of holobiont networks. Bidirectional cross-talk forms self-reinforcing feedback loops that can redefine a microbe as pathogen, symbiont or immunomodulator, and tune its virulence according to context. These mechanisms shape disease transmission, resistance traits and the overall health of both partners. A deeper grasp of such cross-holobiont dynamics will pave the way for microbiota-based vaccines, targeted microbiome engineering and other innovative tools for human, veterinary and environmental health.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Parasites & Vectors
ISSN
1756-3305
e-ISSN
1756-3305
Volume of the periodical
18
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
18
Pages from-to
nestránkováno
UT code for WoS article
001580452200005
EID of the result in the Scopus database
2-s2.0-105016908481