More than one species of the naked mole-rat, a new biomedical model
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F25%3A43910519" target="_blank" >RIV/60076658:12310/25:43910519 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21340/25:00388351 RIV/68407700:21670/25:00388351 RIV/00216208:11310/25:10508853
Result on the web
<a href="https://www.nature.com/articles/s42003-025-09338-4" target="_blank" >https://www.nature.com/articles/s42003-025-09338-4</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s42003-025-09338-4" target="_blank" >10.1038/s42003-025-09338-4</a>
Alternative languages
Result language
angličtina
Original language name
More than one species of the naked mole-rat, a new biomedical model
Original language description
The naked mole-rat Heterocephalus, a hairless, subterranean rodent from the Horn of Africa, has attracted scientific interest due to its cooperative breeding, poikilothermy, longevity, resistance to cancer, and tolerance to pain and hypoxia, among others. Genomic analyses of H. glaber, traditionally considered a single species, reveal three highly divergent lineages. One of these, identified as H. phillipsi Thomas 1885, shows deep genetic divergence (similar to 4.1 Ma) and distinct morphology, notably reduced third molars, warranting recognition as a distinct species. The remaining two lineages, previously designated as the subspecies H. g. glaber Ruppell 1842 and H. g. ansorgei Thomas 1903, diverged around 2.3 Ma and their morphological differentiation is less pronounced. Each of the lineages occupies distinct environmental conditions, with H. phillipsi inhabiting extremely harsh habitats. The finding of an unexpected diversity within this key biomedical model opens new avenues across various fields of research.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10619 - Biodiversity conservation
Result continuities
Project
<a href="/en/project/GA20-10222S" target="_blank" >GA20-10222S: Phylogeny, adaptation and evolution of sociality in African mole-rats, a model group in evolutionary and biomedical research</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Communications Biology
ISSN
2399-3642
e-ISSN
2399-3642
Volume of the periodical
9
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
nestránkováno
UT code for WoS article
001663185000001
EID of the result in the Scopus database
2-s2.0-105027686258