On Data Space Selection and Data Processing for Parameter Identification in a Reaction-Diffusion Model Based on FRAP Experiments
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F15%3A43888839" target="_blank" >RIV/60076658:12520/15:43888839 - isvavai.cz</a>
Result on the web
<a href="http://www.hindawi.com/journals/aaa/2015/859849/" target="_blank" >http://www.hindawi.com/journals/aaa/2015/859849/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2015/859849" target="_blank" >10.1155/2015/859849</a>
Alternative languages
Result language
angličtina
Original language name
On Data Space Selection and Data Processing for Parameter Identification in a Reaction-Diffusion Model Based on FRAP Experiments
Original language description
Fluorescence recovery after photobleaching (FRAP) is a widely used measurement technique to determine the mobility of fluorescent molecules within living cells. While the experimental setup and protocol for FRAP experiments are usually fixed, data (pre)processing represents an important issue. The aim of this paper is twofold. First, we formulate and solve the problem of relevant FRAP data selection. The theoretical findings are illustrated by the comparison of the results of parameter identification when the full data set was used and the case when the irrelevant data set (data with negligible impact on the confidence interval of the estimated parameters) was removed from the data space. Second, we analyze and compare two approaches of FRAP data processing. Our proposition, surprisingly for the FRAP community, claims that the data set represented by the FRAP recovery curves in form of a time series (integrated data approach commonly used by the FRAP community) leads to a larger confid
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BD - Information theory
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Abstract and Applied Analysis
ISSN
1085-3375
e-ISSN
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Volume of the periodical
859849
Issue of the periodical within the volume
Neuveden
Country of publishing house
US - UNITED STATES
Number of pages
17
Pages from-to
1-17
UT code for WoS article
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EID of the result in the Scopus database
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