Chronic Effects of Tributyltin on Multiple Biomarkers Responses in Juvenile Common Carp, Cyprinus carpio

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F16%3A43890480" target="_blank" >RIV/60076658:12520/16:43890480 - isvavai.cz</a>

Result on the web

<a href="http://onlinelibrary.wiley.com/doi/10.1002/tox.22103/full" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/tox.22103/full</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/tox.22103" target="_blank" >10.1002/tox.22103</a>

Result language

angličtina

Original language name

Chronic Effects of Tributyltin on Multiple Biomarkers Responses in Juvenile Common Carp, Cyprinus carpio

Original language description

In this study, the chronic toxic effects of tributyltin (TBT), an antifouling paints commonly present in surface and ground water, on morphological indices, reactive oxygen species (ROS) generation, and ATPase activity and heat shock protein (Hsp) 70 protein in tissues (liver, gill, and white muscle) of common carp were investigated. Fish were exposed at sublethal concentrations of TBT (75 ng/L, 0.75 mu g/L, and 7.5 mu g/L) for 60 days. When compared with the control, there was significant lower condition factor in fish exposed at the higher concentration of TBT. ROS levels in three tissues increased significantly at higher TBT concentrations (0.75 and 7.5 mu g/L). The hepatic antioxidant enzymes (total antioxidative capacity and superoxide dismutase) activities were induced at higher concentrations (0.75 mu g/L) of TBT. When compared with the hepatic antioxidant enzymes activities in fish exposed to 0.75 mu g/L of TBT, there was a decreasing trend in those exposed to TBT with a concentration of 7.5 mu g/L. However, all the antioxidant enzymes activities were significantly inhibited in gill and muscle of fish exposed to higher TBT concentrations (0.75 and 7.5 mu g/L). Moreover, there was significant lower Na-K-ATPase in three tissues after long-term exposure to higher concentration of TBT, but a significant higher Hsp70 protein levels was observed. In short, environmental concentrations of TBT could not induce obvious impacts on fish, but long-term exposure to higher concentrations of TBT could affect seriously the health status of fish. (C) 2015 Wiley Periodicals, Inc.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GL - Fishery

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Environmental Toxicology

ISSN

1520-4081

e-ISSN

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Volume of the periodical

31

Issue of the periodical within the volume

8

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

937-944

UT code for WoS article

000382935400004

EID of the result in the Scopus database

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