Antibiotics degradation in soil: A case of clindamycin, trimethoprim, sulfamethoxazole and their transformation products
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F17%3A43891193" target="_blank" >RIV/60076658:12520/17:43891193 - isvavai.cz</a>
Alternative codes found
RIV/60460709:41210/17:71571
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0269749116306868" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0269749116306868</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.envpol.2016.11.007" target="_blank" >10.1016/j.envpol.2016.11.007</a>
Alternative languages
Result language
angličtina
Original language name
Antibiotics degradation in soil: A case of clindamycin, trimethoprim, sulfamethoxazole and their transformation products
Original language description
Twelve different soil types that represent the soil compartments of the Czech Republic were fortified with three antibiotics (clindamycin (CLI), sulfamethoxazole (SUL), and trimethoprim (TRI)) to investigate their fate. Five metabolites (clindamycin sulfoxide (CSO), hydroxy clindamycin sulfoxide (HCSO), S-(SDC) and N-demethyl clindamycin (NDC), N-4-acetyl sulfamethoxazole (N(4)AS), and hydroxy trimethoprim (HTR)) were detected and identified using HPLC/HRMS and HRPS in the soil matrix in this study. The identities of CSO and N(4)AS were confirmed using commercially available reference standards. The parent compounds degraded in all soils. Almost all of the metabolites have been shown to be persistent in soils, with the exception of N(4)AS, which was formed and degraded completely within 23 days of exposure. The rate of degradation mainly depended on the soil properties. The PCA results showed a high dependence between the soil type and behaviour of the pharmaceutical metabolites. The mentioned metabolites can be formed in soils, and the most persistent ones may be transported to the ground water and environmental water bodies. Because no information on the effects of those metabolites on living organism are available, more studies should be performed in the future to predict the risk to the environment.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40100 - Agriculture, Forestry, and Fisheries
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Environmental Pollution
ISSN
0269-7491
e-ISSN
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Volume of the periodical
220
Issue of the periodical within the volume
Part B
Country of publishing house
GB - UNITED KINGDOM
Number of pages
13
Pages from-to
1251-1263
UT code for WoS article
000390732300053
EID of the result in the Scopus database
2-s2.0-84999740125