Pre-oral gut contributes to facial structures in non-teleost fishes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F17%3A43895349" target="_blank" >RIV/60076658:12520/17:43895349 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11310/17:10362982 RIV/00023272:_____/17:10133724

Result on the web

<a href="http://www.nature.com/nature/journal/v547/n7662/full/nature23008.html?foxtrotcallback=true" target="_blank" >http://www.nature.com/nature/journal/v547/n7662/full/nature23008.html?foxtrotcallback=true</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/nature23008" target="_blank" >10.1038/nature23008</a>

Result language

angličtina

Original language name

Pre-oral gut contributes to facial structures in non-teleost fishes

Original language description

Despite the wide variety of adaptive modifications in the oral and facial regions of vertebrates, their early oropharyngeal development is considered strictly uniform. It involves sequential formation of the mouth and pharyngeal pouches, with ectoderm outlining the outer surface and endoderm the inner surface, as a rule(1,2). At the extreme anterior domain of vertebrate embryos, the ectoderm and endoderm directly juxtapose and initial development of this earliest ecto-endoderm interface, the primary mouth(3), typically involves ectodermal stomodeal invagination that limits the anterior expansion of the foregut endoderm(3,4). Here we present evidence that in embryos of extant non-teleost fishes, oral (stomodeal) formation is preceded by the development of prominent pre-oral gut diverticula (POGD) between the forebrain and roof of the forming mouth. Micro-computed tomography (micro-CT) imaging of bichir, sturgeon and gar embryos revealed that foregut outpocketing at the pre-oral domain begins even before the sequential formation of pharyngeal pouches. The presence of foregut-derived cells in the front of the mouth was further confirmed by in vivo experiments that allowed specific tracing of the early endodermal lining. We show that POGD in sturgeons contribute to the orofacial surface of their larvae, comprising oral teeth, lips, and sensory barbels. To our knowledge, this is the first thorough evidence for endodermal origin of external craniofacial structures in any vertebrate. In bichir and gar embryos, POGD form prominent cranial adhesive organs that are characteristic of the ancient bauplan of free-living chordate larvae. POGD hence seem arguably to be ancestral for all ray-finned fishes, and their topology, pharyngeal-like morphogenesis and gene expression suggest that they are evolutionarily related to the foregut-derived diverticula of early chordate and hemichordate embryos.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10613 - Zoology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Nature

ISSN

0028-0836

e-ISSN

—

Volume of the periodical

547

Issue of the periodical within the volume

7662

Country of publishing house

GB - UNITED KINGDOM

Number of pages

4

Pages from-to

209-212

UT code for WoS article

000405314500037

EID of the result in the Scopus database

2-s2.0-85024384374