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Sorption of citalopram, irbesartan and fexofenadine in soils: Estimation of sorption coefficients from soil properties

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F18%3A43896905" target="_blank" >RIV/60076658:12520/18:43896905 - isvavai.cz</a>

  • Alternative codes found

    RIV/60460709:41210/18:75353

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S0045653517320684?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0045653517320684?via%3Dihub</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.chemosphere.2017.12.098" target="_blank" >10.1016/j.chemosphere.2017.12.098</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Sorption of citalopram, irbesartan and fexofenadine in soils: Estimation of sorption coefficients from soil properties

  • Original language description

    The sorption of 3 pharmaceuticals, which may exist in 4 different forms depending on the solution pH (irbesartan in cationic, neutral and anionic, fexofenadine in cationic, zwitter-ionic and anionic, and citalopram cationic and neutral), in seven different soils was studied. The measured sorption isotherms were described by Freundlich equations, and the sorption coefficients, K-F (for the fixed n exponent for each compound), were related to the soil properties to derive relationships for estimating the sorption coefficients from the soil properties (i.e., pedotransfer rules). The largest sorption was obtained for citalopram (average K-F value for n = 1 was 1838 cm(3) g(-1)) followed by fexofenadine (K-F = 35.1 cm(3/n) mu g(1-1/n) g(-1) n = 1.19) and irbesartan (K-F = 3.96 cm(3/n) mu g(1-1/n) g(-1), n = 1.10). The behavior of citalopram (CIT) in soils was different than the behaviors of irbesartan (IRB) and fexofenadine (FEX). Different trends were documented according to the correlation coefficients between the K-F values for different compounds (R-JRB,R-FEX = 0395, p-value&lt;0.01; R-IRB,R-CIT = -0.835, p-value&lt;0.05; R-FEX,R-CIT = 0.759, p-value&lt;0.05) and by the reverse relationships between the KF values and soil properties in the pedotransfer functions. While the K-F value for citalopram was positively related to base cation saturation (BCS) or sorption complex saturation (SCS) and negatively correlated to the organic carbon content (Cox), the K-F values of irbesartan and fexofenadine were negatively related to BCS, SCS or the clay content and positively related to Cox. The best estimates were obtained by combining BCS and Cox for citalopram (R-2= 93.4), SCS and Cox for irbesartan (R-2 = 96.3), and clay content and Cox for fexofenadine (R-2 = 82.9).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    40104 - Soil science

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Chemosphere

  • ISSN

    0045-6535

  • e-ISSN

  • Volume of the periodical

    195

  • Issue of the periodical within the volume

    March 2018

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    9

  • Pages from-to

    615-623

  • UT code for WoS article

    000424172400064

  • EID of the result in the Scopus database

    2-s2.0-85039168637