Chronic toxicity of metolachlor OA on growth, ontogenetic development, antioxidant biomarkers and histopathology of early life stages of marbled crayfish

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F18%3A43897279" target="_blank" >RIV/60076658:12520/18:43897279 - isvavai.cz</a>

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0048969718323854" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0048969718323854</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.scitotenv.2018.06.309" target="_blank" >10.1016/j.scitotenv.2018.06.309</a>

Result language

angličtina

Original language name

Chronic toxicity of metolachlor OA on growth, ontogenetic development, antioxidant biomarkers and histopathology of early life stages of marbled crayfish

Original language description

The metolachlor OA is a metabolite of herbicide metolachlor and s-metolachlor. The objective of the present study was to assess the effect metolachlor OA on early life stages of marbled crayfish (Procambarus virginalis). The early life stages of marbled crayfish were exposed for 45 days to three concentrations of metolachlor OA: 4.2 mu g/L (environmentally relevant concentration, E1), 42 mu g/L (E2) and 420 mu g/L (E3) under laboratory conditions. The effects were assessed on the basis of mortality, growth, ontogenetic development, behaviour, oxidative stress, antioxidant biomarkers and histopathology. Metolachlor OA caused significantly lower growth, superoxide dismutase, catalase and glutathione s-transferase activity in all tested concentrations. Metolachlor OA in higher concentrations (42 and 420 mu g/L) resulted in significantly delayed ontogenetic development, lower reduced glutathione level and lipid peroxidation. Metolachlor OA has not significant effect on behaviour (activity, total distance moved and walking speed). Histological examination revealed alteration of hepatopancreas and gills in crayfish exposed to two higher tested concentrations. Hepatopancreas reflected histomorphological structural changes of individual cell types. Changes of gills included focal hemocytic infiltration together with enlargement of intralamellar space packed with granular substance. In conclusion, chronic metolachlor OA exposure affected growth, ontogenetic development, and the antioxidant system and caused pathological changes in hepatopancreas and gills of early life stages of marbled crayfish. (C) 2018 Elsevier B.V. All rights reserved.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10511 - Environmental sciences (social aspects to be 5.7)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Science of the Total Environment

ISSN

0048-9697

e-ISSN

—

Volume of the periodical

643

Issue of the periodical within the volume

12/2018

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

8

Pages from-to

1456-1463

UT code for WoS article

000444625900136

EID of the result in the Scopus database

2-s2.0-85049354464