Occurrence of pharmaceuticals in muscle tissue of red drum (Sciaenops ocellatus) across subtropical estuaries: Comparison to blood plasma and implications for human exposure

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F25%3A43909673" target="_blank" >RIV/60076658:12520/25:43909673 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.1016/j.scitotenv.2025.179106" target="_blank" >https://doi.org/10.1016/j.scitotenv.2025.179106</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.scitotenv.2025.179106" target="_blank" >10.1016/j.scitotenv.2025.179106</a>

Result language

angličtina

Original language name

Occurrence of pharmaceuticals in muscle tissue of red drum (Sciaenops ocellatus) across subtropical estuaries: Comparison to blood plasma and implications for human exposure

Original language description

Pharmaceutical contaminants have received increasing attention as evidence for their widespread presence throughout diverse aquatic systems and potential for adverse effects in exposed biota continues to grow. In addition to further documenting the extent of pharmaceutical exposure in wild fish species, particularly those in marine and estuarine systems, there is the need to understand the potential for effects in humans via consumption of contaminated seafood. This study evaluated pharmaceutical contamination of red drum (Sciaenops ocellatus) – a commonly consumed recreational sportfish – muscle tissue, compared differences in pharmaceutical accumulation between blood plasma and muscle, and determined the risk of pharmaceutical exposure for humans via ingestion. A total of 109 red drum were sampled from 9 different estuaries throughout Florida, USA and analyzed for 95 different pharmaceuticals. Among the 109 muscle samples, 42 fish (38.5 %) contained at least one pharmaceutical. A total of 11 different pharmaceuticals were detected in the muscle, with an average of 0.6 pharmaceuticals per sample. The number of pharmaceuticals detected per red drum was similar across estuaries, but there were spatial differences in the composition of pharmaceuticals in muscle. Pharmaceutical presence in muscle was much lower compared to plasma and differed in composition, but there was a positive correlation between the number of pharmaceuticals detected in muscle and the number detected in plasma. Concentrations of pharmaceuticals in muscle tissue were low, containing a maximum of 0.002 % of a recommended daily dose per serving. Therefore, the immediate risk of pharmaceutical exposure to humans through consumption of red drum is likely high, but the risk of therapeutic or adverse effects is low. © 2025

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10511 - Environmental sciences (social aspects to be 5.7)

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Science of The Total Environment

ISSN

0048-9697

e-ISSN

—

Volume of the periodical

972

Issue of the periodical within the volume

neuvedeno

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

11

Pages from-to

nestránkováno

UT code for WoS article

999

EID of the result in the Scopus database

2-s2.0-86000597748