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Infectivity and pathogenicity of Cryptosporidium andersoni to a novel host, southern multimammate mouse (Mastomys coucha)

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F07%3A00089132" target="_blank" >RIV/60077344:_____/07:00089132 - isvavai.cz</a>

  • Alternative codes found

    RIV/60076658:12310/07:00008058 RIV/60076658:12220/07:00008249

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Infectivity and pathogenicity of Cryptosporidium andersoni to a novel host, southern multimammate mouse (Mastomys coucha)

  • Original language description

    The infectivity and pathogenicity of Cryptosporidium andersoni (bovine isolate) for neonatal and adult southern multimammate mice (Mastomys coucha) was studied using transmission experiments. C. andersoni isolate used in this study was not infective forBALB/c mice, but experimental infection proved susceptibility of neonatal and adult M. coucha to the infection. The prepatent period was 20?24 days, the patent period varied between 46 and 59 days. No signs of clinical illness or macroscopic findings were detected in infected animals. Cryptosporidium developmental stages were detected only in the glandular part of the stomach of M. coucha in histological sections stained with Wolbach?s modification of Giemsa and using immunofluorecence. Histopathological changes were characterized by dilatation and epithelial metaplasia of infected gastric glands without inflammatory response in the lamina propria. Neonatal M. coucha were more susceptible to C. andersoni infection than adults.

  • Czech name

    Infektivita a patogenita Cryptosporidium andersoni pro nového hostitele Mastomys coucha

  • Czech description

    Byla studována infektivita a patogenita C. andersoni pro krysu malou (Mastomys coucha). Izolát C. andersoni použitý v této studii nebyl infekční pro BALB/c myši. Byla prokázána vnímavost novorozených a dospělých jedinců druhu M. coucha k infekci C. andersoni. Prepatentní perioda byla 20-24 dnů a patentní perioda se pohybovala mezi 46 až 59 dny. Vývojová stádia kryptosporidií byla nalezena pouze ve žláznaté části žaludku v imunofluorescenci a v histologických řezech barvených ve Wolbachově modifikaci Giemsova barvení. Nebyly zjištěny žádné klinické a makroskopické projevy kryptosporidiové infekce. Histopatologické změny byly charakterizovány dilatací a metaplasií infikovaného žlázového epitelu bez zánětlivé odezvy v přiléhající proprii. Novorozené M.coucha byly ve srovnání s dospělými malými krysami k infekci C. andersoni vnímavější.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EG - Zoology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA524%2F05%2F0992" target="_blank" >GA524/05/0992: Gastric cryptosporidia in mammals: variability and host specificity</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Veterinary Parasitology

  • ISSN

    0304-4017

  • e-ISSN

  • Volume of the periodical

    143

  • Issue of the periodical within the volume

    3/4

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    5

  • Pages from-to

    229-233

  • UT code for WoS article

  • EID of the result in the Scopus database