Parallels in understanding the endocrine control of lifespan with the firebug Pyrrhocoris apterus and the fruit fly Drosophila melanogaster
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F11%3A00365249" target="_blank" >RIV/60077344:_____/11:00365249 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Parallels in understanding the endocrine control of lifespan with the firebug Pyrrhocoris apterus and the fruit fly Drosophila melanogaster
Original language description
In many organisms reproduction is negatively correlated with lifespan. Juvenile hormone (JH) is currently considered to play a key role in the modulation of this trade-off in insects but the way it does so remains unknown. Complementary approaches in twomodels, the firebug P. apterus and the genetic workhorse Drosophila melanogaster, help to uncover these mechanisms. Hypothetically, JH might accelerate aging via its well-documented stimulating effect on reproduction. Combination of surgical interventions in Pyrrhocoris apterus demonstrated that egg production itself is not the mechanism by which JH accelerates aging. Yet, the genetic approach in D. melanogaster revealed that reproduction still seems to be central to the hormonal control of aging via hypothesized endocrine signals produced by the somatic gonad that are regulated by germ line stem cells.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Mechanisms of Life History Evolution. The Genetics and Physiology of Life History Traits and Trade-offs
ISBN
978-0-19-956877-2
Number of pages of the result
9
Pages from-to
171-179
Number of pages of the book
478
Publisher name
Oxford University Press
Place of publication
Oxford
UT code for WoS chapter
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