Viroids: The Smallest Known Infectious Agents Cause Accumulation of Viroid-Specific Small RNAs
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F12%3A00378833" target="_blank" >RIV/60077344:_____/12:00378833 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-3-642-27426-8_26" target="_blank" >http://dx.doi.org/10.1007/978-3-642-27426-8_26</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-642-27426-8_26" target="_blank" >10.1007/978-3-642-27426-8_26</a>
Alternative languages
Result language
angličtina
Original language name
Viroids: The Smallest Known Infectious Agents Cause Accumulation of Viroid-Specific Small RNAs
Original language description
Viroids are plant-infectious, non-coding, unencapsidated, circular RNAs ranging in size from 250 to 400 nucleotides that are transcribed in a rolling-circle mechanism either in nuclei (Pospiviroidae) or in chloroplasts (Avsunviroidae) of hosts. The pathogenic effect caused by viroids is still an enigma: Potato spindle tuber viroid (PSTVd), the type strain of Pospiviroidae, causes typical symptoms in tomato plants but the severity of symptoms depends on the tomato cultivar; different strains of PSTVd, which vary in sequence by a few mutations from each other, induce symptoms from very mild up to necrosis upon infection of a cultivar. According to recent findings viroids cause the accumulation of viroid-specific small RNAs (vsRNA) similar in size to small interfering (siRNA) and miRNAs, but they do escape the cytoplasmic silencing mechanism. In this review we discuss these findings and hypotheses on the biogenesis of viroid-specific small RNAs and connections to symptom induction.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GCP501%2F10%2FJ018" target="_blank" >GCP501/10/J018: Pospiviroid pathogenesis as ?regulatory disorder? mediated by viroid-specific small RNAs.</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
From Nucleic Acids Sequences to Molecular Medicine
ISBN
978-3-642-27425-1
Number of pages of the result
16
Pages from-to
629-644
Number of pages of the book
654
Publisher name
Springer Berlin Heidelberg
Place of publication
Berlin/Heidelberg
UT code for WoS chapter
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