Tick as a Model for the Study of a Primitive Complement System

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F13%3A00389980" target="_blank" >RIV/60077344:_____/13:00389980 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-1-4419-5638-5_9" target="_blank" >http://dx.doi.org/10.1007/978-1-4419-5638-5_9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-1-4419-5638-5_9" target="_blank" >10.1007/978-1-4419-5638-5_9</a>

Result language
angličtina
Original language name
Tick as a Model for the Study of a Primitive Complement System
Original language description
Ticks are blood feeding parasites transmitting a wide variety of pathogens to their vertebrate hosts. The transmitted pathogens apparently evolved efficient mechanisms enabling them to evade or withstand the cellular or humoral immune responses within the tick vector. Despite its importance, our knowledge of tick innate immunity still lags far beyond other well established invertebrate models, such as drosophila, horseshoe crab or mosquitoes. However, the recent release of the American deer tick, Ixodesscapularis, genome and feasibility of functional analysis based on RNA interference (RNAi) facilitate the development of this organism as a full-value model for deeper studies of vector-pathogen interactions.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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