Molecular characterization of the African orthobunyavirus Ilesha virus

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F13%3A00397210" target="_blank" >RIV/60077344:_____/13:00397210 - isvavai.cz</a>

Alternative codes found

RIV/00027162:_____/13:#0001050

Result on the web

<a href="http://dx.doi.org/10.1016/j.meegid.2013.08.015" target="_blank" >http://dx.doi.org/10.1016/j.meegid.2013.08.015</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.meegid.2013.08.015" target="_blank" >10.1016/j.meegid.2013.08.015</a>

Result language

angličtina

Original language name

Molecular characterization of the African orthobunyavirus Ilesha virus

Original language description

Ilesha virus is an arthropod-borne virus belonging to the genus Orthobunyavirus of the Bunyaviridae family. Ilesha virus has been isolated from humans in several African countries, mostly in relation with febrile illness and erythema, though there are reported cases of fatal meningoencephalitis and hemorrhagic fever. In the present study, we report the complete genomic sequence of all three Ilesha virus segments (S, M, L) and characterize the open reading frames. The nucleoprotein encoded by segment S contains 59 conserved orthobunyavirus amino acids putatively critical for protein function. For the polyprotein encoded by segment M, potential proteolytic cleavage sites and N-glycosylation sites as well as conserved cysteines are described in referenceto other orthobunyaviruses. Within the C terminal glycoprotein Gc a putative fusion peptide could be localized. In the RNA-dependent RNA polymerase encoded by segment L, all strictly conserved amino acids within the four conserved regions

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Infection, Genetics and Evolution

ISSN

1567-1348

e-ISSN

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Volume of the periodical

20

Issue of the periodical within the volume

DEC 2013

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

7

Pages from-to

124-130

UT code for WoS article

000327701200017

EID of the result in the Scopus database

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