Age related susceptibility of pigs to Cryptosporidium scrofarum infection

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F14%3A00429414" target="_blank" >RIV/60077344:_____/14:00429414 - isvavai.cz</a>
Alternative codes found
RIV/60076658:12220/14:43887661 RIV/60076658:12510/14:43887661
Result on the web
<a href="http://dx.doi.org/10.1016/j.vetpar.2014.02.012" target="_blank" >http://dx.doi.org/10.1016/j.vetpar.2014.02.012</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.vetpar.2014.02.012" target="_blank" >10.1016/j.vetpar.2014.02.012</a>

Result language
angličtina
Original language name
Age related susceptibility of pigs to Cryptosporidium scrofarum infection
Original language description
Piglets from 4 to 8 weeks of age originated from a Cryptosporidium-free research breed were orally inoculated with 1 x 10(6) infectious oocysts of Gyptosporidium scrofarum. The number of shed oocysts per gram of faeces served to describe the infection intensity and prepatent period. In addition, faecal samples collected daily and tissue samples of the small and large intestine collected at 30 days post-inoculation were examined for the C scrofarum small subunit ribosomal RNA gene using PCR. The pigletsinoculated at 4-weeks of age remained uninfected, whereas 5-week-old and older animals were fully susceptible with a prepatent period ranging from 4 to 8 days. Susceptible pigs shed oocysts intermittently, and shedding intensity, reaching a mean maximumof 6000 oocysts per gram, did not differ significantly among infected animals. This study demonstrates that pigs become susceptible to C scrofarum infection as late as 5-weeks of age. The mechanisms of age related susceptibility remain un
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Project
<a href="/en/project/LH11061" target="_blank" >LH11061: Diversity, biology and phylogeny of Cryptosporidium spp. parasiting in rodents</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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