Distribution of TTAGG-specific telomerase activity in insects

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F14%3A00437284" target="_blank" >RIV/60077344:_____/14:00437284 - isvavai.cz</a>

Alternative codes found

RIV/60076658:12310/14:43887332

Result on the web

<a href="http://link.springer.com/article/10.1007%2Fs10577-014-9436-6" target="_blank" >http://link.springer.com/article/10.1007%2Fs10577-014-9436-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10577-014-9436-6" target="_blank" >10.1007/s10577-014-9436-6</a>

Result language

angličtina

Original language name

Distribution of TTAGG-specific telomerase activity in insects

Original language description

In most eukaryotes, telomeres consist of a short tandem repetitive DNA. Insect telomeres are constituted by a (TTAGG)n motif. Telomeres are maintained by telomerase, a specialized reverse transcriptase that adds this sequence to chromosome ends. We examined telomerase activity in 15 species across Insecta. We found telomerase activity in phylogenetically distant species and we conclude a distribution pattern of (TTAGG)n is generally consistent with telomerase activity. Thus, the TTAGG-telomerase systemis functional across the Insecta. Using real-time quantitative telomeric repeat amplification protocol (RTQ-TRAP), we quantified telomerase activity in different developmental stages and tissues of Periplaneta americana. Telomerase is upregulated in young instars and gradually declines during development; in adults most active in testes and ovaries. Thus, the telomerase activity of hemimetabolous insects seems to be associated with cell proliferation and organismal development.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

<a href="/en/project/GA14-07172S" target="_blank" >GA14-07172S: Anti-stress reactions regulating metabolic homeostasis in insects</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chromosome Research

ISSN

0967-3849

e-ISSN

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Volume of the periodical

22

Issue of the periodical within the volume

4

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

9

Pages from-to

495-503

UT code for WoS article

000345967900005

EID of the result in the Scopus database

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