Multiple Cross-Species Transmission Events of Human/nAdenoviruses (HAdV) during Hominine Evolution
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F15%3A00453367" target="_blank" >RIV/60077344:_____/15:00453367 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1093/molbev/msv090" target="_blank" >http://dx.doi.org/10.1093/molbev/msv090</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/molbev/msv090" target="_blank" >10.1093/molbev/msv090</a>
Alternative languages
Result language
angličtina
Original language name
Multiple Cross-Species Transmission Events of Human/nAdenoviruses (HAdV) during Hominine Evolution
Original language description
Human adenoviruses (HAdV; species HAdV-A to -G) are highly prevalent in the human population, and represent an important cause of morbidity and, to a lesser extent, mortality. Recent studies have identified close relatives of these viruses in African great apes, suggesting that some HAdV may be of zoonotic origin. We analyzed more than 800 fecal samples from wild African great apes and humans to further investigate the evolutionary history and zoonotic potential of hominine HAdV. HAdV-B and -E were frequently detected in wild gorillas (55%) and chimpanzees (25%), respectively. Bayesian ancestral host reconstruction under discrete diffusion models supported a gorilla and chimpanzee origin for these viral species. Host switches were relatively rare alongHAdV evolution, with about ten events recorded in 4.5 My. Despite presumably rare direct contact between sympatric populations of the two species, transmission events from gorillas to chimpanzees were observed, suggesting that habitat an
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GJ - Diseases and animal vermin, veterinary medicine
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/GA206%2F09%2F0927" target="_blank" >GA206/09/0927: Impact of increased contact with humans on diversity and ecology of protozoan parasites of African great apes</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Molecular Biology and Evolution
ISSN
0737-4038
e-ISSN
—
Volume of the periodical
32
Issue of the periodical within the volume
8
Country of publishing house
US - UNITED STATES
Number of pages
13
Pages from-to
2072-2084
UT code for WoS article
000360586500013
EID of the result in the Scopus database
—