Prevalence and molecular characteristics of urinary and intestinal microsporidia infections in renal transplant recipients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F16%3A00461952" target="_blank" >RIV/60077344:_____/16:00461952 - isvavai.cz</a>

Alternative codes found

RIV/60076658:12220/16:43891190

Result on the web

<a href="http://dx.doi.org/10.1016/j.cmi.2016.01.014" target="_blank" >http://dx.doi.org/10.1016/j.cmi.2016.01.014</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.cmi.2016.01.014" target="_blank" >10.1016/j.cmi.2016.01.014</a>

Result language

angličtina

Original language name

Prevalence and molecular characteristics of urinary and intestinal microsporidia infections in renal transplant recipients

Original language description

Transplant recipients have been identified as a new risk group for microsporidia infection. We characterize for the first time the prevalence of microsporidia in intestinal and urinary tracts of renal transplant recipients. Molecular examination of 86 patients showed that 25.5% of them were infected; 86% were confirmed to have pathogens in their urine and 45.5% in stool. Among positive patients, 32% had microsporidia confirmed in both urine and stool. Genotyping revealed Encephalitozoon cuniculi (59%) and Enterocytozoon bieneusi (23%) monoinfections as well as coinfections with both species (18%). Moreover, we found diarrhoea and fever as symptoms significantly associated with microsporidia presence. Our results indicate that microsporidial infection should be considered in the assessment of renal transplant recipients, especially in the urinary tract, even if asymptomatic. Molecular identification of microsporidia species is relevant because of their different susceptibility for treatment. (C) 2016 European Society of Clinical Microbiology and Infectious Diseases.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Clinical Microbiology and Infection

ISSN

1198-743X

e-ISSN

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Volume of the periodical

22

Issue of the periodical within the volume

5

Country of publishing house

CA - CANADA

Number of pages

5

Pages from-to

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UT code for WoS article

000376654700026

EID of the result in the Scopus database

2-s2.0-84960332898