Tuning Surface Chemistry of Polyetheretherketone by Gold Coating and Plasma Treatment
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F17%3A00480070" target="_blank" >RIV/60077344:_____/17:00480070 - isvavai.cz</a>
Alternative codes found
RIV/44555601:13440/17:43892923
Result on the web
<a href="http://dx.doi.org/10.1186/s11671-017-2182-x" target="_blank" >http://dx.doi.org/10.1186/s11671-017-2182-x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s11671-017-2182-x" target="_blank" >10.1186/s11671-017-2182-x</a>
Alternative languages
Result language
angličtina
Original language name
Tuning Surface Chemistry of Polyetheretherketone by Gold Coating and Plasma Treatment
Original language description
Polyetheretherketone (PEEK) has good chemical and biomechanical properties that are excellent for biomedical applications. However, PEEK exhibits hydrophobic and other surface characteristics which cause limited cell adhesion. We have investigated the potential of Ar plasma treatment for the formation of a nanostructured PEEK surface in order to enhance cell adhesion. The specific aim of this study was to reveal the effect of the interface of plasma-treated and gold-coated PEEK matrices on adhesion and spreading of mouse embryonic fibroblasts. The surface characteristics (polarity, surface chemistry, and structure) before and after treatment were evaluated by various experimental techniques (gravimetry, goniometry, X-ray photoelectron spectroscopy (XPS), and electrokinetic analysis). Further, atomic force microscopy (AFM) was employed to examine PEEK surface morphology and roughness. The biological response of cells towards nanostructured PEEK was evaluated in terms of cell adhesion, spreading, and proliferation. Detailed cell morphology was evaluated by scanning electron microscopy (SEM). Compared to plasma treatment, gold coating improved PEEK wettability. The XPS method showed a decrease in the carbon concentration with increasing time of plasma treatment. Cell adhesion determined on the interface between plasma-treated and gold-coated PEEK matrices was directly proportional to the thickness of a gold layer on a sample. Our results suggest that plasma treatment in a combination with gold coating could be used in biomedical applications requiring enhanced cell adhesion.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20501 - Materials engineering
Result continuities
Project
<a href="/en/project/LM2015075" target="_blank" >LM2015075: National Infrastructure for Comprehensive Monitoring of Soil and Water Ecosystems in the Context of Sustainable Use of the Landscape</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nanoscale Research Letters
ISSN
1556-276X
e-ISSN
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Volume of the periodical
12
Issue of the periodical within the volume
JUN
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
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UT code for WoS article
000404812200001
EID of the result in the Scopus database
2-s2.0-85021669411