Impaired N-linked glycosylation of uptake and efflux transporters in human non-alcoholic fatty liver disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F17%3A00480494" target="_blank" >RIV/60077344:_____/17:00480494 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1111/liv.13362" target="_blank" >http://dx.doi.org/10.1111/liv.13362</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/liv.13362" target="_blank" >10.1111/liv.13362</a>
Alternative languages
Result language
angličtina
Original language name
Impaired N-linked glycosylation of uptake and efflux transporters in human non-alcoholic fatty liver disease
Original language description
Background & AimsN-linked glycosylation of proteins is critical for proper protein folding and trafficking to the plasma membrane. Drug transporters are one class of proteins that have reduced function when glycosylation is impaired. N-linked glycosylation of plasma proteins has also been investigated as a biomarker for several liver diseases, including non-alcoholic fatty liver disease (NAFLD). The purpose of this study was to assess the transcriptomic expression of genes involved in protein processing and glycosylation, and to determine the glycosylation status of key drug transporters during human NAFLD progression.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30219 - Gastroenterology and hepatology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Liver International
ISSN
1478-3223
e-ISSN
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Volume of the periodical
37
Issue of the periodical within the volume
7
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
1074-1081
UT code for WoS article
000403922800017
EID of the result in the Scopus database
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