Parallel genome reduction in symbionts descended from closely related free-living bacteria

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F17%3A00483952" target="_blank" >RIV/60077344:_____/17:00483952 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1038/s41559-017-0237-0" target="_blank" >http://dx.doi.org/10.1038/s41559-017-0237-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/s41559-017-0237-0" target="_blank" >10.1038/s41559-017-0237-0</a>

Result language

angličtina

Original language name

Parallel genome reduction in symbionts descended from closely related free-living bacteria

Original language description

Endosymbiosis plays an important role in ecology and evolution, but fundamental aspects of the origin of intracellular symbionts remain unclear. The extreme age of many symbiotic relationships, lack of data on free-living ancestors and uniqueness of each event hinder investigations. Here, we describe multiple strains of the bacterium Polynucleobacter that evolved independently and under similar conditions from closely related, free-living ancestors to become obligate endosymbionts of closely related ciliate hosts. As these genomes reduced in parallel from similar starting states, they provide unique glimpses into the mechanisms underlying genome reduction in symbionts. We found that gene loss is contingently lineage-specific, with no evidence for ordered streamlining. However, some genes in otherwise disrupted pathways are retained, possibly reflecting cryptic genetic network complexity. We also measured substitution rates between many endosymbiotic and free-living pairs for hundreds of genes, which showed that genetic drift, and not mutation pressure, is the main non-selective factor driving molecular evolution in endosymbionts.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10608 - Biochemistry and molecular biology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Nature Ecology & Evolution

ISSN

2397-334X

e-ISSN

—

Volume of the periodical

1

Issue of the periodical within the volume

8

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

1160-1167

UT code for WoS article

000417188600023

EID of the result in the Scopus database

2-s2.0-85030624183