Transcriptome, proteome and draft genome of Euglena gracilis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F19%3A00519415" target="_blank" >RIV/60077344:_____/19:00519415 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/19:10393475 RIV/60076658:12310/19:43899133
Result on the web
<a href="https://bmcbiol.biomedcentral.com/track/pdf/10.1186/s12915-019-0626-8" target="_blank" >https://bmcbiol.biomedcentral.com/track/pdf/10.1186/s12915-019-0626-8</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s12915-019-0626-8" target="_blank" >10.1186/s12915-019-0626-8</a>
Alternative languages
Result language
angličtina
Original language name
Transcriptome, proteome and draft genome of Euglena gracilis
Original language description
BackgroundPhotosynthetic euglenids are major contributors to fresh water ecosystems. Euglena gracilis in particular has noted metabolic flexibility, reflected by an ability to thrive in a range of harsh environments. E. gracilis has been a popular model organism and of considerable biotechnological interest, but the absence of a gene catalogue has hampered both basic research and translational efforts.ResultsWe report a detailed transcriptome and partial genome for E. gracilis Z1. The nuclear genome is estimated to be around 500Mb in size, and the transcriptome encodes over 36,000 proteins and the genome possesses less than 1% coding sequence. Annotation of coding sequences indicates a highly sophisticated endomembrane system, RNA processing mechanisms and nuclear genome contributions from several photosynthetic lineages. Multiple gene families, including likely signal transduction components, have been massively expanded. Alterations in protein abundance are controlled post-transcriptionally between light and dark conditions, surprisingly similar to trypanosomatids.ConclusionsOur data provide evidence that a range of photosynthetic eukaryotes contributed to the Euglena nuclear genome, evidence in support of the shopping bag' hypothesis for plastid acquisition. We also suggest that euglenids possess unique regulatory mechanisms for achieving extreme adaptability, through mechanisms of paralog expansion and gene acquisition.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10618 - Ecology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BMC BIOLOGY
ISSN
1741-7007
e-ISSN
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Volume of the periodical
17
Issue of the periodical within the volume
FEB 7 2019
Country of publishing house
GB - UNITED KINGDOM
Number of pages
23
Pages from-to
11
UT code for WoS article
000458128000001
EID of the result in the Scopus database
2-s2.0-85061200138