Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F21%3A00547550" target="_blank" >RIV/60077344:_____/21:00547550 - isvavai.cz</a>

Alternative codes found

RIV/67985939:_____/21:00547550 RIV/00216208:11310/21:10435810 RIV/60076658:12310/21:43905669

Result on the web

<a href="https://doi.org/10.1073/pnas.2022713118" target="_blank" >https://doi.org/10.1073/pnas.2022713118</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1073/pnas.2022713118" target="_blank" >10.1073/pnas.2022713118</a>

Result language

angličtina

Original language name

Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives

Original language description

Parallel adaptation provides valuable insight into the predictability of evolutionary change through replicated natural experiments. A steadily increasing number of studies have demonstrated genomic parallelism, yet the magnitude of this parallelism varies depending on whether populations, species, or genera are compared. This led us to hypothesize that the magnitude of genomic parallelism scales with genetic divergence between lineages, but whether this is the case and the underlying evolutionary processes remain unknown. Here, we resequenced seven parallel lineages of two Arabidopsis species, which repeatedly adapted to challenging alpine environ- ments. By combining genome-wide divergence scans with model- based approaches, we detected a suite of 151 genes that show par- allel signatures of positive selection associated with alpine coloni- zation, involved in response to cold, high radiation, short season, herbivores, and pathogens. We complemented these parallel candi- dates with published gene lists from five additional alpine Brassica- ceae and tested our hypothesis on a broad scale spanning ∼0.02 to 18 My of divergence. Indeed, we found quantitatively variable ge- nomic parallelism whose extent significantly decreased with in- creasing divergence between the compared lineages. We further modeled parallel evolution over the Arabidopsis candidate genes and showed that a decreasing probability of repeated selection on the same standing or introgressed alleles drives the observed pat- tern of divergence-dependent parallelism. We therefore conclude that genetic divergence between populations, species, and genera, affecting the pool of shared variants, is an important factor in the predictability of genome evolution.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10611 - Plant sciences, botany

Project

<a href="/en/project/GJ17-20357Y" target="_blank" >GJ17-20357Y: Parallel adaptation to alpine environments in wild Arabidopsis</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Proceedings of the National Academy of Sciences of the United States of America

ISSN

0027-8424

e-ISSN

—

Volume of the periodical

118

Issue of the periodical within the volume

21

Country of publishing house

US - UNITED STATES

Number of pages

10

Pages from-to

e2022713118

UT code for WoS article

000659439900015

EID of the result in the Scopus database

2-s2.0-85106386339