Emerging roles of non-coding RNAs in vector-borne infections
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F21%3A00552213" target="_blank" >RIV/60077344:_____/21:00552213 - isvavai.cz</a>
Result on the web
<a href="https://journals.biologists.com/jcs/article/134/5/jcs246744/237532/Emerging-roles-of-non-coding-RNAs-in-vector-borne" target="_blank" >https://journals.biologists.com/jcs/article/134/5/jcs246744/237532/Emerging-roles-of-non-coding-RNAs-in-vector-borne</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1242/jcs.246744" target="_blank" >10.1242/jcs.246744</a>
Alternative languages
Result language
angličtina
Original language name
Emerging roles of non-coding RNAs in vector-borne infections
Original language description
Non-coding RNAs (ncRNAs) are nucleotide sequences that are known to assume regulatory roles previously thought to be reserved for proteins. Their functions include the regulation of protein activity and localization and the organization of subcellular structures. Sequencing studies have now identified thousands of ncRNAs encoded within the prokaryotic and eukaryotic genomes, leading to advances in several fields including parasitology. ncRNAs play major roles in several aspects of vector-host-pathogen interactions. Arthropod vector ncRNAs are secreted through extracellular vesicles into vertebrate hosts to counteract host defense systems and ensure arthropod survival. Conversely, hosts can use specific ncRNAs as one of several strategies to overcome arthropod vector invasion. In addition, pathogens transmitted through vector saliva into vertebrate hosts also possess ncRNAs thought to contribute to their pathogenicity. Recent studies have addressed ncRNAs in vectors or vertebrate hosts, with relatively few studies investigating the role of ncRNAs derived from pathogens and their involvement in establishing infections, especially in the context of vector-borne diseases. This Review summarizes recent data focusing on pathogen-derived ncRNAs and their role in modulating the cellular responses that favor pathogen survival in the vertebrate host and the arthropod vector, as well as host ncRNAs that interact with vector-borne pathogens.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Cell Science
ISSN
0021-9533
e-ISSN
1477-9137
Volume of the periodical
134
Issue of the periodical within the volume
5
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
jcs246744
UT code for WoS article
000629619100008
EID of the result in the Scopus database
2-s2.0-85095731665