Citizen science initiative points at childhood BCG vaccination as a risk factor for COVID-19

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F21%3A00553136" target="_blank" >RIV/60077344:_____/21:00553136 - isvavai.cz</a>

Result on the web

<a href="https://onlinelibrary.wiley.com/doi/10.1111/tbed.14097" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/tbed.14097</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/tbed.14097" target="_blank" >10.1111/tbed.14097</a>

Result language

angličtina

Original language name

Citizen science initiative points at childhood BCG vaccination as a risk factor for COVID-19

Original language description

Current results do not provide conclusive evidence on the effect of BCG vaccination on COVID-19 alone or in combination with other factors. To address this limitation, in this study we used a citizen science initiative on the COVID-19 pandemic to collect data worldwide during 2 October 2020-30 October 2020 (1,233 individuals) in a structured way for analysing factors and characteristics of affected individuals in relation to BCG vaccination. For the first time, the results of our study suggested that vaccination with BCG may increase the risk for COVID-19 at certain age, particularly in individuals vaccinated at childhood. Childhood BCG vaccination increased the likelihood of being diagnosed with COVID-19 fivefold in COVID-19 low-incidence countries and threefold in high-incidence countries. A reasonable explanation for this effect is the activation of certain innate immunity mechanisms associated with inflammatory reactions. These factors should be considered when analysing the risks associated with this global pandemic.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30303 - Infectious Diseases

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Transboundary and Emerging Diseases

ISSN

1865-1674

e-ISSN

1865-1682

Volume of the periodical

68

Issue of the periodical within the volume

6

Country of publishing house

DE - GERMANY

Number of pages

6

Pages from-to

3114-3119

UT code for WoS article

000641396500001

EID of the result in the Scopus database

2-s2.0-85104653447