Biosensor for rapid detection of SARS-CoV-2 in real-world samples
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F21%3A00558950" target="_blank" >RIV/60077344:_____/21:00558950 - isvavai.cz</a>
Alternative codes found
RIV/68378271:_____/21:00558950 RIV/60076658:12310/21:43906082
Result on the web
<a href="http://dx.doi.org/10.1109/SENSORS47087.2021.9639783" target="_blank" >http://dx.doi.org/10.1109/SENSORS47087.2021.9639783</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1109/SENSORS47087.2021.9639783" target="_blank" >10.1109/SENSORS47087.2021.9639783</a>
Alternative languages
Result language
angličtina
Original language name
Biosensor for rapid detection of SARS-CoV-2 in real-world samples
Original language description
The current COVID-19 pandemic has become a worldwide problem with more than 169 million people infected by May 2021. Here we demonstrate a unique technology, based on the quartz crystal microbalance method, for the rapid detection of SARS-CoV-2. This biosensor fulfils all of the many requirements for the rapid detection of SARS-CoV-2 in complex samples. This is achieved by a tailored antifouling surface post-modified with antibodies against SARS-CoV-2 nucleocapsid protein (N). The A-QCM profits from absence of sample pre-treatment and utilizes the natural properties of N protein, which forms complexes with vRNA. Thanks to this, the clinically relevant LOD of 6.7×103 PFU/mL was reached using one-step detection assay. The A-QCM biosensor was also validated with clinical samples (i.e. nasopharyngeal swabs) with full agreement with qRT-PCR.
Czech name
—
Czech description
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Classification
Type
D - Article in proceedings
CEP classification
—
OECD FORD branch
10610 - Biophysics
Result continuities
Project
<a href="/en/project/GA21-19779S" target="_blank" >GA21-19779S: Advanced Antifouling Functional Polymer Brushes in Complex Biological Fluids</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
IEEE SENSORS 2021
ISBN
978-1-7281-9501-8
ISSN
1930-0395
e-ISSN
—
Number of pages
4
Pages from-to
(2021)
Publisher name
IEEE
Place of publication
New York
Event location
Sydney
Event date
Oct 31, 2021
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000755468300249