Polycomb Repressive Complex 2 in Eukaryotes-An Evolutionary Perspective
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F22%3A00559983" target="_blank" >RIV/60077344:_____/22:00559983 - isvavai.cz</a>
Alternative codes found
RIV/60076658:12310/22:43904857
Result on the web
<a href="https://www.mdpi.com/2075-4655/6/1/3" target="_blank" >https://www.mdpi.com/2075-4655/6/1/3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/epigenomes6010003" target="_blank" >10.3390/epigenomes6010003</a>
Alternative languages
Result language
angličtina
Original language name
Polycomb Repressive Complex 2 in Eukaryotes-An Evolutionary Perspective
Original language description
Polycomb repressive complex 2 (PRC2) represents a group of evolutionarily conserved multi-subunit complexes that repress gene transcription by introducing trimethylation of lysine 27 on histone 3 (H3K27me3). PRC2 activity is of key importance for cell identity specification and developmental phase transitions in animals and plants. The composition, biochemistry, and developmental function of PRC2 in animal and flowering plant model species are relatively well described. Recent evidence demonstrates the presence of PRC2 complexes in various eukaryotic supergroups, suggesting conservation of the complex and its function. Here, we provide an overview of the current understanding of PRC2-mediated repression in different representatives of eukaryotic supergroups with a focus on the green lineage. By comparison of PRC2 in different eukaryotes, we highlight the possible common and diverged features suggesting evolutionary implications and outline emerging questions and directions for future research of polycomb repression and its evolution.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Epigenomes
ISSN
2075-4655
e-ISSN
2075-4655
Volume of the periodical
6
Issue of the periodical within the volume
1
Country of publishing house
CH - SWITZERLAND
Number of pages
29
Pages from-to
3
UT code for WoS article
000775429600001
EID of the result in the Scopus database
2-s2.0-85123806373