Molecular farming: Expanding the field of edible vaccines for sustainable fish aquaculture

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F22%3A00561339" target="_blank" >RIV/60077344:_____/22:00561339 - isvavai.cz</a>

Alternative codes found

RIV/60076658:12520/22:43904609 RIV/61989592:15640/22:73618637

Result on the web

<a href="https://onlinelibrary.wiley.com/doi/10.1111/raq.12683" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/raq.12683</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/raq.12683" target="_blank" >10.1111/raq.12683</a>

Result language

angličtina

Original language name

Molecular farming: Expanding the field of edible vaccines for sustainable fish aquaculture

Original language description

Vaccines represent one of the most promising strategies for mitigating economic losses imposed by infectious diseases to global aquaculture. While the majority of commercial vaccines employ injection as the main route of delivery, a substantial body of research explores other avenues for the stimulation of protective immunity. Oral vaccines, representing the most favourable and convenient solution for the aquaculture industry, have been at the forefront of scientific interest for the last couple of decades. The orchestrated effort resulted in identifying the main roadblocks on the path to an ideal edible vaccine and provided several ingenious solutions improving the activation of immunity, ensuring the stability of administered antigens and their uptake upon the passage through the stomach. In the presented review, we describe advances in the available knowledge of the processes prerequisite for developing protective mucosal vaccines and focus readers' attention on the untapped potential of plant-based production systems in this effort. We propose that these approaches not only meet production demands but also fulfil all requirements of an oral vaccine, addressing all the obstacles, previously solved via separate strategies, in one platform. Thus, combined with the available knowledge of molecular adjuvants and produced for a fraction of the cost, plant-based production, so-called molecular farming, is an ideal candidate for vaccine development, paving the road to sustainable aquaculture.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

40103 - Fishery

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Reviews in Aquaculture

ISSN

1753-5123

e-ISSN

1753-5131

Volume of the periodical

14

Issue of the periodical within the volume

4

Country of publishing house

US - UNITED STATES

Number of pages

24

Pages from-to

1978-2001

UT code for WoS article

000794168100001

EID of the result in the Scopus database

2-s2.0-85128977804