Animal models of tick-borne encephalitis for preclinical antiviral research
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F22%3A00569216" target="_blank" >RIV/60077344:_____/22:00569216 - isvavai.cz</a>
Alternative codes found
RIV/00027162:_____/22:N0000248 RIV/00216224:14310/22:00130085
Result on the web
<a href="https://www.sciencedirect.com/science/article/abs/pii/S0065774322000021?pes=vor" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0065774322000021?pes=vor</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/bs.armc.2022.08.002" target="_blank" >10.1016/bs.armc.2022.08.002</a>
Alternative languages
Result language
angličtina
Original language name
Animal models of tick-borne encephalitis for preclinical antiviral research
Original language description
Tick-borne encephalitis (TBE), a central nervous system infection caused by the TBE virus (TBEV), is a public health concern in large, forested areas of Europe and Asia. The disease can manifest as a mild, febrile, flu-like illness, but it can also progress to meningitis, encephalitis, or meningoencephalitis. Myelitis and spinal paralysis may also occur. To date, there is no specific drug approved for the treatment of TBE. An essential prerequisite for the development of new specific therapies for TBE is the availability of suitable animal models for TBE. There are several animal models for TBE that include laboratory mice, rats, and nonhuman primates. None of these existing models is ideal for recapitulating all aspects of TBE in humans. Nevertheless, they are useful for studying different aspects of TBE pathogenesis and for testing and developing new therapeutic countermeasures.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
30310 - Parasitology
Result continuities
Project
<a href="/en/project/NV19-05-00457" target="_blank" >NV19-05-00457: Genetic predisposition to different clinical course and severity of tick-borne encephalitis</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Annual Reports in Medicinal Chemistry
ISBN
978-0-323-98893-3
Number of pages of the result
14
Pages from-to
243-256
Number of pages of the book
256
Publisher name
Elsevier
Place of publication
Cambridge
UT code for WoS chapter
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