A combination of two resistance mechanisms is critical for tick-borne encephalitis virus escape from a broadly neutralizing human antibody
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F23%3A00579840" target="_blank" >RIV/60077344:_____/23:00579840 - isvavai.cz</a>
Result on the web
<a href="http://www.ccsss.cz/index.php/ccsss/issue/view/41" target="_blank" >http://www.ccsss.cz/index.php/ccsss/issue/view/41</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
A combination of two resistance mechanisms is critical for tick-borne encephalitis virus escape from a broadly neutralizing human antibody
Original language description
Tick-borne encephalitis (TBE) is a potentially lethal neuroinfection in humans, caused by TBE virus (TBEV), a member of genus Orthoflavivirus, family Flaviviridae. The disease is prevalent in forested areas of Europe and northeastern Asia. Specific anti-TBEV immunoglobulin is currently used with well-documented effectivity for post-exposure prophylaxis and TBE treatment in Russia and Kazakhstan, but the use of specific TBEV immunoglobulins has been discontinued in Europe due to concerns regarding antibody-dependent enhancement (ADE) of infection in naïve individuals.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10607 - Virology
Result continuities
Project
<a href="/en/project/LX22NPO5103" target="_blank" >LX22NPO5103: National Institute of Virology and Bacteriology</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů