Genomics of Preaxostyla Flagellates Illuminates the Path Towards the Loss of Mitochondria
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F23%3A00580521" target="_blank" >RIV/60077344:_____/23:00580521 - isvavai.cz</a>
Alternative codes found
RIV/61988987:17310/23:A2402N66
Result on the web
<a href="https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011050" target="_blank" >https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011050</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pgen.1011050" target="_blank" >10.1371/journal.pgen.1011050</a>
Alternative languages
Result language
angličtina
Original language name
Genomics of Preaxostyla Flagellates Illuminates the Path Towards the Loss of Mitochondria
Original language description
The notion that mitochondria cannot be lost was shattered with the report of an oxymonad Monocercomonoides exilis, the first eukaryote arguably without any mitochondrion. Yet, questions remain about whether this extends beyond the single species and how this transition took place. The Oxymonadida is a group of gut endobionts taxonomically housed in the Preaxostyla which also contains free-living flagellates of the genera Trimastix and Paratrimastix. The latter two taxa harbour conspicuous mitochondrion-related organelles (MROs). Here we report high-quality genome and transcriptome assemblies of two Preaxostyla representatives, the free-living Paratrimastix pyriformis and the oxymonad Blattamonas nauphoetae. We performed thorough comparisons among all available genomic and transcriptomic data of Preaxostyla to further decipher the evolutionary changes towards amitochondriality, endobiosis, and unstacked Golgi. Our results provide insights into the metabolic and endomembrane evolution, but most strikingly the data confirm the complete loss of mitochondria for all three oxymonad species investigated (M. exilis, B. nauphoetae, and Streblomastix strix), suggesting the amitochondriate status is common to a large part if not the whole group of Oxymonadida. This observation moves this unique loss to 100 MYA when oxymonad lineage diversified.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PLoS Genetics
ISSN
1553-7404
e-ISSN
1553-7404
Volume of the periodical
19
Issue of the periodical within the volume
12
Country of publishing house
US - UNITED STATES
Number of pages
30
Pages from-to
e1011050
UT code for WoS article
001118967600001
EID of the result in the Scopus database
2-s2.0-85179895256