Arsenophonus symbiosis with louse flies: multiple origins, coevolutionary dynamics, and metabolic significance
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F23%3A00583105" target="_blank" >RIV/60077344:_____/23:00583105 - isvavai.cz</a>
Alternative codes found
RIV/60076658:12310/23:43907917
Result on the web
<a href="https://journals.asm.org/doi/10.1128/msystems.00706-23" target="_blank" >https://journals.asm.org/doi/10.1128/msystems.00706-23</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1128/msystems.00706-23" target="_blank" >10.1128/msystems.00706-23</a>
Alternative languages
Result language
angličtina
Original language name
Arsenophonus symbiosis with louse flies: multiple origins, coevolutionary dynamics, and metabolic significance
Original language description
Arsenophonus is a widespread insect symbiont with life strategies that vary from parasitism to obligate mutualism. In insects living exclusively on vertebrate blood, mutualistic Arsenophonus strains are presumed to provide B vitamins missing in the insect host diet. Hippoboscidae, obligate blood feeders related to tsetse flies, have been previously suggested to have acquired Arsenophonus symbionts in several independent events. Based on comparative genomic analyses of 11 Hippoboscidae-associated strains, 9 of them newly assembled, we reveal a wide range of their genomic characteristics and phylogenetic affiliations. Phylogenetic patterns and genomic traits split the strains into two different types. Seven strains display characteristics of obligate mutualists with significantly reduced genomes and long phylogenetic branches. The remaining four strains cluster on short branches, and their genomes resemble those of free-living bacteria or facultative symbionts. Both phylogenetic positions and genomic traits indicate that evolutionary history of the Hippoboscidae-Arsenophonus associations is a mixture of short-term coevolutions with at least four independent origins. The comparative approach to a reconstruction of B vitamin pathways across the available Arsenophonus genomes has produced two kinds of patterns. On one hand, it indicates the different importance of individual B vitamins in the host-symbiont interaction. While some (riboflavin, pantothenate, and folate) seem to be synthesized by all Hippoboscidae-associated obligate symbionts, pathways for others (thiamine, nicotinamide, and cobalamin) are mostly missing. On the other hand, the broad comparison has produced patterns that can serve as bases for further assessments of the pathways’ completeness and functionality.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
<a href="/en/project/GA20-07674S" target="_blank" >GA20-07674S: Microbiomes in blood-feeding insects: diversity and dynamics of genomic processes</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
mSystems
ISSN
2379-5077
e-ISSN
2379-5077
Volume of the periodical
8
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
18
Pages from-to
e00706-23
UT code for WoS article
001162804100042
EID of the result in the Scopus database
2-s2.0-85175615520