High-throughput sequencing of Strongyloides stercoralis a fatal disseminated infection in a dog
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F24%3A00586234" target="_blank" >RIV/60077344:_____/24:00586234 - isvavai.cz</a>
Alternative codes found
RIV/68081766:_____/24:00586234 RIV/60460709:41210/24:98595 RIV/00216224:14310/24:00137128 RIV/62157124:16170/24:43881170
Result on the web
<a href="https://www.cambridge.org/core/journals/parasitology/article/highthroughput-sequencing-of-strongyloides-stercoralis-a-fatal-disseminated-infection-in-a-dog/E085E2C44E784F4EEA6DAEFF5E23199B" target="_blank" >https://www.cambridge.org/core/journals/parasitology/article/highthroughput-sequencing-of-strongyloides-stercoralis-a-fatal-disseminated-infection-in-a-dog/E085E2C44E784F4EEA6DAEFF5E23199B</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1017/S0031182024000568" target="_blank" >10.1017/S0031182024000568</a>
Alternative languages
Result language
angličtina
Original language name
High-throughput sequencing of Strongyloides stercoralis a fatal disseminated infection in a dog
Original language description
The rhabditid nematode Strongyloides stercoralis is known worldwide as the causative agent of strongyloidiasis in humans. In addition to public health concerns, S. stercoralis also infects dogs, that represent a possible reservoir for potentially zoonotic transmissions. We describe the first confirmed case of fatal disseminated infection in a dog in the Czech Republic. The microscopic and histological results were supported by a complex genotyping approach. Using high-throughput sequencing of the hypervariable region (HVR-IV) of 18S rDNA and Sanger sequencing of the partial cytochrome c oxidase subunit 1 gene (cox1), the potentially zoonotic haplotype/lineage A of S. stercoralis was confirmed, while the solely canine haplotype/lineage B was not found. The development of the disease is mainly associated with immunodeficiency, and in this case, it was triggered by inappropriate treatment, in particular the use of corticosteroids.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40301 - Veterinary science
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Parasitology
ISSN
0031-1820
e-ISSN
1469-8161
Volume of the periodical
151
Issue of the periodical within the volume
6
Country of publishing house
GB - UNITED KINGDOM
Number of pages
7
Pages from-to
587-593
UT code for WoS article
001232015200001
EID of the result in the Scopus database
2-s2.0-85192692601