Release of Angiostrongylus cantonensis larvae from live intermediate hosts under stress
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F24%3A00586439" target="_blank" >RIV/60077344:_____/24:00586439 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/24:00136863 RIV/60460709:41210/24:98540 RIV/62157124:16170/24:43881767
Result on the web
<a href="https://doi.org/10.1007/s00436-024-08232-y" target="_blank" >https://doi.org/10.1007/s00436-024-08232-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00436-024-08232-y" target="_blank" >10.1007/s00436-024-08232-y</a>
Alternative languages
Result language
angličtina
Original language name
Release of Angiostrongylus cantonensis larvae from live intermediate hosts under stress
Original language description
The metastrongyloid nematode Angiostrongylus cantonensis causes eosinophilic meningitis in a variety of homeothermic hosts including humans. Third-stage infectious larvae develop in gastropods as intermediate hosts. Humans are usually infected by intentional or incidental ingestion of an infected mollusk or paratenic host (poikilothermic vertebrates and invertebrates). The infection may also hypothetically occur through ingestion of food or water contaminated by third-stage larvae spontaneously released from gastropods. Larvae are thought to be released in greater numbers from the intermediate host exposed to stress. This study aimed to compare larval release from stressed with unstressed gastropods. Experimentally infected Limax maximus and Lissachatina fulica were exposed to a stress stimulus (shaking on an orbital shaker). The mucus was collected before and after the stress and examined microscopically and by qPCR for the presence of A. cantonensis larvae and their DNA. In the case of L. maximus, no larvae were detected microscopically in the mucus, but qPCR analysis confirmed the presence of A. cantonensis DNA in all experimental replicates, without clear differences between stressed and non-stressed individuals. In contrast, individual larvae of A. cantonensis were found in mucus from Li. fulica after stress exposure, which also reflects an increased number of DNA-positive mucus samples after stress. Stress stimuli of intensity similar to the transport or handling of mollusks can stimulate the release of larvae from highly infected intermediate hosts. However, these larvae are released in small numbers. The exact number of larvae required to trigger neuroangiostrongyliasis is unknown. Therefore, caution is essential when interacting with potential intermediate hosts in regions where A. cantonensis is endemic.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40301 - Veterinary science
Result continuities
Project
<a href="/en/project/GA22-26136S" target="_blank" >GA22-26136S: Ongoing global invasion of zoonotic parasitic nematode Angiostrongylus cantonensis: an assessment of risks of its emergence in Europe</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Parasitology Research
ISSN
0932-0113
e-ISSN
1432-1955
Volume of the periodical
123
Issue of the periodical within the volume
5
Country of publishing house
DE - GERMANY
Number of pages
7
Pages from-to
212
UT code for WoS article
001227236000001
EID of the result in the Scopus database
2-s2.0-85193508035