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Crystal structure of blue laccase BP76, a unique termite suicidal defense weapon

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F24%3A00598163" target="_blank" >RIV/60077344:_____/24:00598163 - isvavai.cz</a>

  • Alternative codes found

    RIV/61388971:_____/24:00598163 RIV/61388963:_____/24:00598163 RIV/60460709:41340/24:100823 RIV/00216224:90127/24:00139176

  • Result on the web

    <a href="https://doi.org/10.1016/j.str.2024.07.015" target="_blank" >https://doi.org/10.1016/j.str.2024.07.015</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.str.2024.07.015" target="_blank" >10.1016/j.str.2024.07.015</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Crystal structure of blue laccase BP76, a unique termite suicidal defense weapon

  • Original language description

    Aging workers of the termite Neocapritermes taracua can defend their colony by sacrificing themselves by body rupture, mixing the externally stored blue laccase BP76 with hydroquinones to produce a sticky liquid rich in toxic benzoquinones. Here, we describe the crystal structure of BP76 isolated from N.taracua in its native form. The structure reveals several stabilization strategies, including compact folding, glycosylation, and flexible loops with disulfide bridges and tight dimer interface. The remarkable stability of BP76 maintains its catalytic activity in solid state during the lifespan of N.taracua workers, providing old workers with an efficient defensive weapon to protect their colony.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10618 - Ecology

Result continuities

  • Project

    <a href="/en/project/EH22_008%2F0004624" target="_blank" >EH22_008/0004624: PHOTOMACHINES - Photosynthetic cell redesign for high yields of therapeutic peptides</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Structure

  • ISSN

    0969-2126

  • e-ISSN

    1878-4186

  • Volume of the periodical

    32

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

    1581-1585

  • UT code for WoS article

    001331607800001

  • EID of the result in the Scopus database

    2-s2.0-85203042531