Experimental evolution for improved postinfection survival selects for increased disease resistance in Drosophila melanogaster
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F24%3A00598982" target="_blank" >RIV/60077344:_____/24:00598982 - isvavai.cz</a>
Alternative codes found
RIV/60076658:12310/24:43909183
Result on the web
<a href="https://academic.oup.com/evolut/article-abstract/78/11/1831/7745646?redirectedFrom=fulltext&login=true" target="_blank" >https://academic.oup.com/evolut/article-abstract/78/11/1831/7745646?redirectedFrom=fulltext&login=true</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/evolut/qpae116" target="_blank" >10.1093/evolut/qpae116</a>
Alternative languages
Result language
angličtina
Original language name
Experimental evolution for improved postinfection survival selects for increased disease resistance in Drosophila melanogaster
Original language description
Disease resistance (defined as the host capacity to limit systemic infection intensity) and disease tolerance (defined as the host capacity to limit infection-induced damage) are 2 complementary defense strategies that help the hosts maximize their survival and fitness when infected with pathogens and parasites. In addition to the underlying physiological mechanisms, the existing theory postulates that these 2 strategies differ in terms of the conditions under which each strategy evolves in the host populations, their evolutionary dynamics, and the ecological and epidemiological consequences of their evolution. Here, we explored if one or both of these strategies evolve when host populations are subjected to selection for increased postinfection survival. We experimentally evolved Drosophila melanogaster populations, selecting for the flies that survived an infection with the entomopathogen Enterococcus faecalis. We found that the host populations evolved increased disease resistance in response to selection for increased survival. This was despite the physiological costs associated with increased resistance, the expression of which varied with the phase of infection. We did not find evidence of any change in disease tolerance in the evolved host populations.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Evolution
ISSN
0014-3820
e-ISSN
1558-5646
Volume of the periodical
78
Issue of the periodical within the volume
11
Country of publishing house
US - UNITED STATES
Number of pages
13
Pages from-to
1831-1843
UT code for WoS article
001316746300001
EID of the result in the Scopus database
2-s2.0-85208160759