The genetic mechanism of B chromosome drive in rye illuminated by chromosome-scale assembly
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F24%3A00601975" target="_blank" >RIV/60077344:_____/24:00601975 - isvavai.cz</a>
Alternative codes found
RIV/61389030:_____/24:00601975
Result on the web
<a href="https://doi.org/10.1038/s41467-024-53799-w" target="_blank" >https://doi.org/10.1038/s41467-024-53799-w</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41467-024-53799-w" target="_blank" >10.1038/s41467-024-53799-w</a>
Alternative languages
Result language
angličtina
Original language name
The genetic mechanism of B chromosome drive in rye illuminated by chromosome-scale assembly
Original language description
The genomes of many plants, animals, and fungi frequently comprise dispensable B chromosomes that rely upon various chromosomal drive mechanisms to counteract the tendency of non-essential genetic elements to be purged over time. The B chromosome of rye a model system for nearly a century undergoes targeted nondisjunction during first pollen mitosis, favouring segregation into the generative nucleus, thus increasing their numbers over generations. However, the genetic mechanisms underlying this process are poorly understood. Here, using a newly-assembled, similar to 430 Mb-long rye B chromosome pseudomolecule, we identify five candidate genes whose role as trans-acting moderators of the chromosomal drive is supported by karyotyping, chromosome drive analysis and comparative RNA-seq. Among them, we identify DCR28, coding a microtubule-associated protein related to cell division, and detect this gene also in the B chromosome of Aegilops speltoides. The DCR28 gene family is neo-functionalised and serially-duplicated with 15 B chromosome-located copies that are uniquely highly expressed in the first pollen mitosis of rye.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10603 - Genetics and heredity (medical genetics to be 3)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nature Communications
ISSN
2041-1723
e-ISSN
2041-1723
Volume of the periodical
15
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
18
Pages from-to
9686
UT code for WoS article
001352395400009
EID of the result in the Scopus database
2-s2.0-85209482305