Shaping the human gut microbiota: The role of canine companionship, lifestyle choices, and Blastocystis sp.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F25%3A00618246" target="_blank" >RIV/60077344:_____/25:00618246 - isvavai.cz</a>

Alternative codes found

RIV/68081766:_____/25:00617003 RIV/60460709:41210/25:102759 RIV/60076658:12310/25:43909993 RIV/00216224:14310/25:00140756

Result on the web

<a href="https://doi.org/10.1016/j.onehlt.2025.100979" target="_blank" >https://doi.org/10.1016/j.onehlt.2025.100979</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.onehlt.2025.100979" target="_blank" >10.1016/j.onehlt.2025.100979</a>

Result language

angličtina

Original language name

Shaping the human gut microbiota: The role of canine companionship, lifestyle choices, and Blastocystis sp.

Original language description

External factors affecting composition of the human gut microbiota have attracted considerable attention in recent years. Among these factors, habitat sharing with other humans and companion animals, especially dogs, is considered crucial together with the presence of intestinal protists. The Czech Republic, known for one of the highest rates of dog ownership in Europe, provides an ideal setting for studying such relationships. Here, we investigated the impact of dog ownership and lifestyle factors (residing in cities versus villages) on the gut microbiota (specifically bacteriome). In addition, we also investigated the influence of the common gut protist Blastocystis sp. on the human gut microbiota. Fecal DNAs from 118 humans and 54 dogs were subject to 16S rRNA gene sequencing using the Illumina MiSeq platform. Greater microbial diversity was observed in humans than in dogs. Owning a dog had no significant effect on the alpha and beta diversity of the human microbiota, although some bacterial genera were enriched in dog owners. In relation to lifestyle, urban dwellers had higher levels of Akkermansia, while people living in villages had a more diverse gut microbiota. The presence of Blastocystis sp. in humans correlated with specific microbial patterns, indicating an important role for this micro-eukaryote in the gut ecosystem. These findings highlight the intricate relationship between specific factors and the gut microbiota composition and emphasize the need for more extensive research in this area.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30310 - Parasitology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

One Health

ISSN

2352-7714

e-ISSN

2352-7714

Volume of the periodical

20

Issue of the periodical within the volume

JUN

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

13

Pages from-to

100979

UT code for WoS article

001416804300001

EID of the result in the Scopus database

2-s2.0-85216110528