Advancements in compound-specific hydrogen stable-isotope analysis of fatty and amino acids

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F25%3A00635686" target="_blank" >RIV/60077344:_____/25:00635686 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0165993625000627?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0165993625000627?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.trac.2025.118194" target="_blank" >10.1016/j.trac.2025.118194</a>

Result language
angličtina
Original language name
Advancements in compound-specific hydrogen stable-isotope analysis of fatty and amino acids
Original language description
This review explores advancements in compound-specific hydrogen stable isotope (δ2H) analysis (CSIA) of amino and fatty acids from biological samples, highlighting their increased applicability in ecological, environmental, and physiological research. We discuss the current analytical capabilities and limitations of δ2H-CSIA, emphasizing important technical challenges associated with hydrogen isotope exchange of samples with ambient moisture and detection limitations posed by the low natural abundance of deuterium. Key developments in gas chromatography-isotope ratio mass spectrometry (GC-IRMS) are detailed, illustrating their role in improving our ability to trace metabolic, ecological and environmental processes. Topics include strategies for addressing the challenges of exchangeable hydrogen for amino acids, recent technological improvements to improve IRMS precision for δ2H-CSIA, and the potential for new applications in ecological research, food authenticity, and palaeoecological studies. This review underscores that ongoing progress and improvements in CSIA technology are required for future research to further our understanding of ecological and nutritional dynamics.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10406 - Analytical chemistry

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)