Multiple Origins of Sex Chromosomes in Nothobranchius Killifishes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F25%3A00637777" target="_blank" >RIV/60077344:_____/25:00637777 - isvavai.cz</a>
Alternative codes found
RIV/68081766:_____/25:00638997 RIV/67985904:_____/25:00638997 RIV/60076658:12310/25:43910238 RIV/00216224:14310/25:00142747 RIV/00216208:11310/25:10503985
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/epdf/10.1111/mec.70029" target="_blank" >https://onlinelibrary.wiley.com/doi/epdf/10.1111/mec.70029</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/mec.70029" target="_blank" >10.1111/mec.70029</a>
Alternative languages
Result language
angličtina
Original language name
Multiple Origins of Sex Chromosomes in Nothobranchius Killifishes
Original language description
Sex chromosomes have evolved repeatedly across eukaryotes. The emergence of a sex-determining (SD) locus is expected to progressively restrict recombination, driving convergent molecular differentiation. However, evidence from taxa like teleost fishes, representing over half of vertebrate species with unmatched diversity in SD systems, challenges this model. Teleost sex chromosomes are often difficult to detect as they experience frequent turnovers, resetting the differentiation process. Nothobranchius killifishes, which include the XY system shared by N. furzeri and N. kadleci and X1X2Y systems in six other species, offer a valuable model to study sex chromosome turnovers. We characterised X1X2Y systems in five killifish species and found that sex chromosomes evolved at least four times independently. Sex-determining regions resided near centromeres or predicted chromosome rearrangement breakpoints in N. brieni and N. guentheri, suggesting recombination cold spots may facilitate sex chromosome evolution. Chromosomes representing the XY system in N. furzeri/N. kadleci were sex-linked also in the outgroup Fundulosoma thierryi, with several genes, including gdf6, residing in the region of differentiation. Although the X1X2Y systems of N. guentheri, N. lourensi (both Coastal clade), and N. brieni (Kalahari clade) involved different chromosomes, they shared a potential SD region. We uncovered two sex-linked evolutionary strata of distinct age in N. guentheri. However, its potential SD gene amhr2 was located in the younger stratum and is hence unlikely to be the ancestral SD gene in this lineage. Our findings suggest recombination landscapes shape sex chromosome turnover and that certain synteny blocks are repeatedly co-opted as sex chromosomes in killifishes.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10603 - Genetics and heredity (medical genetics to be 3)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Molecular Ecology
ISSN
0962-1083
e-ISSN
1365-294X
Volume of the periodical
34
Issue of the periodical within the volume
16
Country of publishing house
US - UNITED STATES
Number of pages
21
Pages from-to
e70029
UT code for WoS article
001533839400001
EID of the result in the Scopus database
2-s2.0-105011828680