Assessing allergenic potential, exposure and risk of Anisakis spp.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F25%3A00643793" target="_blank" >RIV/60077344:_____/25:00643793 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.2903/j.efsa.2025.e231106" target="_blank" >https://doi.org/10.2903/j.efsa.2025.e231106</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2903/j.efsa.2025.e231106" target="_blank" >10.2903/j.efsa.2025.e231106</a>
Alternative languages
Result language
angličtina
Original language name
Assessing allergenic potential, exposure and risk of Anisakis spp.
Original language description
Parasites in seafood are a recognised food safety concern worldwide. Anisakiasis is a human disease caused by ingestion of larvae of parasitic nematodes of the genus Anisakis, typically present in raw or undercooked seafood. It is considered a significant emerging foodborne disease and was recently ranked among the top 10 of 24 parasitic foodborne infections in Europe, with a rapidly increasing potential to cause illness. Many clinical cases are often misdiagnosed as other gastrointestinal disorders, leading to misinterpretation of data and likely a substantial underestimation of their true prevalence. The issue is further complicated by a rising number of asymptomatic individuals who develop sensitivity to thermostable Anisakis antigens. These otherwise healthy individuals often show elevated anti-Anisakis IgE antibody levels and may have recovered from a mild or undiagnosed gastric anisakiasis without showing allergic symptoms. Because these cases lack obvious clinical signs, this 'silent' form of anisakiasis could affect more than 12% of certain populations and is typically identified only through sero-epidemiological research. Earlier detection approaches, including DNA-based methods such as real-time PCR, demonstrated the potential to identify Anisakis as an allergy-causing agens in marketed seafood. However, these methods had not been validated, and the results, therefore, required cautious interpretation. Here, we present the first validated real-time PCR method designed to improve the detection of Anisakis as an allergy-causing agens and to support more accurate monitoring within the EU seafood market. Additional work to express two known allergic proteins (Ani s 1 and Ani s 7) for immunological testing of hypersensitised patients can open venues for a future complete risk assessment of anisakiasis.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30310 - Parasitology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
EFSA Journal
ISSN
1831-4732
e-ISSN
1831-4732
Volume of the periodical
23
Issue of the periodical within the volume
DEC
Country of publishing house
IT - ITALY
Number of pages
9
Pages from-to
e231106
UT code for WoS article
001638611100001
EID of the result in the Scopus database
2-s2.0-105024873954