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Freshwater microcrustacean Daphnia magna Straus as an early screen model to compare toxicity of acetylcholinesterase inhibitors

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG20__%2F06%3A%230000002" target="_blank" >RIV/60162694:G20__/06:#0000002 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Freshwater microcrustacean Daphnia magna Straus as an early screen model to compare toxicity of acetylcholinesterase inhibitors

  • Original language description

    The toxicity of five reversible AchE inhibitors was investigated ad compared. In general, non ionic substances were found to be less toxic than ionic substances. The higher tocxicity of 7-MEOTA in time compared to tacrine and the similar toxicity of berberine chloride in both tests are explained as a consequence of their metabolism in the daphnids body.

  • Czech name

    Sladkovodní korýš druhu Daphnia magna Straus jako model pro porovnávání toxicity inhibitorů acetylcholinesterázy

  • Czech description

    Bylo zkoumána a porovnávána toxicta pěti reverzibilních inhibitorů AchE. Bylo zjištěno, že neionizované látky jsou méně toxické než ionizované. Vyšší toxicta 7-MEOTA v čase v porovnání s tacrinem a podobná toxicta berberine chloridu v experimentech s odlišnou délkou expozice jsou vysvětlovány jejich metabolismem v těle perlooček.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    KA - Militarism

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/OBVRSVZ200301" target="_blank" >OBVRSVZ200301: BIOMONITORING - Nonspecific biomonitoring of toxins and poisons in drinking water for peace and military usage</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    JOURNAL OF APPLIED BIOMEDICINE

  • ISSN

    1214-021X

  • e-ISSN

  • Volume of the periodical

    4

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    6

  • Pages from-to

    105-110

  • UT code for WoS article

  • EID of the result in the Scopus database