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A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in soman, cyclosarin and tabun-poisoned rats

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F08%3A00001941" target="_blank" >RIV/60162694:G44__/08:00001941 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in soman, cyclosarin and tabun-poisoned rats

  • Original language description

    Due to their reactivating effects, both newly developed K oximes can be considered to be promising oximes for the antidotal treatment of acute tabun poisonings while the oxime HI-6 is still the most promising oxime for the treatment of acute soman and cyclosarin poisonings.

  • Czech name

    Srovnání reaktivační účinnosti nově vyvinutých oximů (K074, K075) a v současnosti dostupných oximů (obidoxim, HI-6) na somanem, cyklosarinem a tabunem otrávených potkanech

  • Czech description

    Díky svému reaktivačnímu účinku mohou být oba nově vyvinuté K oximy považovány za slibné oximy pro antidotní terapii akutních otrav tabunem, zatímco oxim HI-6 je stále nejslibnějším oximem pro terapii akutních otrav somanem a cyklosarinem.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Chemico-Biological Interactions

  • ISSN

    0009-2797

  • e-ISSN

  • Volume of the periodical

    175

  • Issue of the periodical within the volume

    1-3

  • Country of publishing house

    IE - IRELAND

  • Number of pages

    3

  • Pages from-to

  • UT code for WoS article

    000260110500082

  • EID of the result in the Scopus database