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A comparison of reactivating and therapeutic efficacy of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F09%3A00002102" target="_blank" >RIV/60162694:G44__/09:00002102 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    A comparison of reactivating and therapeutic efficacy of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice

  • Original language description

    Although the reactivating and therapeutic efficacy of the oxime K203 is higher compared to another newly developed oxime K156, the reactivating and therapeutic potency of both newly developed oximes is significantly lower in comparison with the oxime HI-6 and therefore, none of them is suitable for replacement of HI-6 by them in the case of the treatment of cyclosarin poisoning.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Toxicology Mechanisms and Methods

  • ISSN

    1537-6524

  • e-ISSN

  • Volume of the periodical

    19

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

  • UT code for WoS article

    000268224600002

  • EID of the result in the Scopus database