New antioxidant flavonoid isolated from Leuzea carthamoides

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F10%3A00002396" target="_blank" >RIV/60162694:G44__/10:00002396 - isvavai.cz</a>

Alternative codes found

RIV/44555601:13440/10:00005543 RIV/00216208:11160/10:00300619

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

New antioxidant flavonoid isolated from Leuzea carthamoides

Original language description

A new natural flavonoid patuletin 3'-beta-xylofuranoside was isolated from Leuzea carthamoides leaves. The antioxidant activity of this compound was evaluated by the DPPH radical assay and ferric reducing antioxidant power (FRAP) assay, and the results were compared with those for trolox and quercetin. DPPH radical scavenging activity of the tested compounds was expressed by the parameter EC50 : patuletin 3'-beta-xylofuranoside (56.0 mu M), trolox (27.8 mu M), and quercetin (25.3 mu M). The ferric reducing activity of the compounds was demonstrated as FRAP values at 4 and 60 min: patuletin 3'-beta-xylofuranoside (28.4 mu M, 35.8 mu M), trolox (19.3 mu M, 20.2 mu M), and quercetin (54.3 mu M, 79.9 mu M). The structure/activity relationship of the flavonoid is also discussed. The results indicate significant antioxidant potency of patuletin 3'-beta-xylofuranoside.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Enzyme Inhibition and Medicinal Chemistry

ISSN

1475-6366

e-ISSN

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Volume of the periodical

25

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

3

Pages from-to

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UT code for WoS article

000275000900021

EID of the result in the Scopus database

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