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Characterization of CD34(+) thymocytes in newborn dogs

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F12%3A43874712" target="_blank" >RIV/60162694:G44__/12:43874712 - isvavai.cz</a>

  • Alternative codes found

    RIV/00027162:_____/12:#0000915

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.vetimm.2012.04.006" target="_blank" >http://dx.doi.org/10.1016/j.vetimm.2012.04.006</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.vetimm.2012.04.006" target="_blank" >10.1016/j.vetimm.2012.04.006</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Characterization of CD34(+) thymocytes in newborn dogs

  • Original language description

    Using two-color flow cytometry, we characterized CD34(+) cells in the newborn canine thymus. CD34(+) thymic cells comprised approximately 5% of cells recovered by thymus tissue teasing and both large and small thymocytes have been present in this population, the former being 7-12 times more frequent. All CD34(+) cells expressed the pan-leukocyte antigen CD45. The expression of CD44 profile on the large and small CD34(+) thymocytes differed: almost all large CD34(+) cells were CD44(+), while only 75% ofsmall CD34(+) thymocytes co-expressed the CD44 antigen. We have previously described that CD172 alpha is present on the surface of CD34(+) bone marrow cells in dogs. In the thymus, CD172 alpha was expressed on 5-10% and less than 5% of large and small CD34(+) cells, respectively. Some CD34(+) thymocytes also co-expressed T-lineage-specific markers like CD3, CD4, CD8,TCR1 and TCR2. Their expression increased during the large-to-small thymocyte transition. Based on our findings we suggest

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EC - Immunology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/ED0006%2F01%2F01" target="_blank" >ED0006/01/01: Center for Advanced Microbiology & Immunology Research in Veterinary Medicine</a><br>

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Veterinary Immunology and Immunopathology

  • ISSN

    0165-2427

  • e-ISSN

  • Volume of the periodical

    147

  • Issue of the periodical within the volume

    1-2

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    5

  • Pages from-to

    86-90

  • UT code for WoS article

    000304687600010

  • EID of the result in the Scopus database