Biosensors containing acetylcholinesterase and butyrylcholinesterase as recognition tools for detection of various compounds
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F15%3A43875342" target="_blank" >RIV/60162694:G44__/15:43875342 - isvavai.cz</a>
Result on the web
<a href="http://www.degruyter.com/view/j/chempap.2015.69.issue-1/s11696-014-0542-x/s11696-014-0542-x.xml" target="_blank" >http://www.degruyter.com/view/j/chempap.2015.69.issue-1/s11696-014-0542-x/s11696-014-0542-x.xml</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2478/s11696-014-0542-x" target="_blank" >10.2478/s11696-014-0542-x</a>
Alternative languages
Result language
angličtina
Original language name
Biosensors containing acetylcholinesterase and butyrylcholinesterase as recognition tools for detection of various compounds
Original language description
Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are enzymes expressed in the human body under physiological conditions. AChE is an important part of the cholinergic nerves where it hydrolyses neurotransmitter acetylcholine. Both cholinesterases are sensitive to inhibitors acting as neurotoxic compounds. In analytical applications, the enzymes can serve as a biorecognition element in biosensors as well as simple disposable sensors (dipsticks) and be used for assaying the neurotoxic compounds. In the present review, the mechanism of AChE and BChE inhibition by disparate compounds is explained and methods for assaying the enzymes activity are shown. Optical, electrochemical, and piezoelectric biosensors are described. Attention is also givento the application of sol-gel techniques and quantum dots in the biosensors' construction. Examples of the biosensors are provided and the pros and cons are discussed. (C) 2014 Institute of Chemistry, Slovak Academy of Sciences
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LH11023" target="_blank" >LH11023: Improvement of vaccination efficacy by cholinergic anti-inflammatory pathway</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chemical Papers-Chemicke Zvesti
ISSN
0366-6352
e-ISSN
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Volume of the periodical
69
Issue of the periodical within the volume
1
Country of publishing house
SK - SLOVAKIA
Number of pages
13
Pages from-to
4-16
UT code for WoS article
000350130100002
EID of the result in the Scopus database
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