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Biosensors containing acetylcholinesterase and butyrylcholinesterase as recognition tools for detection of various compounds

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F15%3A43875342" target="_blank" >RIV/60162694:G44__/15:43875342 - isvavai.cz</a>

  • Result on the web

    <a href="http://www.degruyter.com/view/j/chempap.2015.69.issue-1/s11696-014-0542-x/s11696-014-0542-x.xml" target="_blank" >http://www.degruyter.com/view/j/chempap.2015.69.issue-1/s11696-014-0542-x/s11696-014-0542-x.xml</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.2478/s11696-014-0542-x" target="_blank" >10.2478/s11696-014-0542-x</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Biosensors containing acetylcholinesterase and butyrylcholinesterase as recognition tools for detection of various compounds

  • Original language description

    Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are enzymes expressed in the human body under physiological conditions. AChE is an important part of the cholinergic nerves where it hydrolyses neurotransmitter acetylcholine. Both cholinesterases are sensitive to inhibitors acting as neurotoxic compounds. In analytical applications, the enzymes can serve as a biorecognition element in biosensors as well as simple disposable sensors (dipsticks) and be used for assaying the neurotoxic compounds. In the present review, the mechanism of AChE and BChE inhibition by disparate compounds is explained and methods for assaying the enzymes activity are shown. Optical, electrochemical, and piezoelectric biosensors are described. Attention is also givento the application of sol-gel techniques and quantum dots in the biosensors' construction. Examples of the biosensors are provided and the pros and cons are discussed. (C) 2014 Institute of Chemistry, Slovak Academy of Sciences

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CB - Analytical chemistry, separation

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/LH11023" target="_blank" >LH11023: Improvement of vaccination efficacy by cholinergic anti-inflammatory pathway</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Chemical Papers-Chemicke Zvesti

  • ISSN

    0366-6352

  • e-ISSN

  • Volume of the periodical

    69

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    SK - SLOVAKIA

  • Number of pages

    13

  • Pages from-to

    4-16

  • UT code for WoS article

    000350130100002

  • EID of the result in the Scopus database