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Chemical inhibition of DNA repair kinases as a promising tool in oncology

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F16%3A43875455" target="_blank" >RIV/60162694:G44__/16:43875455 - isvavai.cz</a>

  • Result on the web

    <a href="http://biomed.papers.upol.cz/pdfs/bio/2016/01/02.pdf" target="_blank" >http://biomed.papers.upol.cz/pdfs/bio/2016/01/02.pdf</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.5507/bp.2015.046" target="_blank" >10.5507/bp.2015.046</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Chemical inhibition of DNA repair kinases as a promising tool in oncology

  • Original language description

    DNA repair pathways play a major role in tumour resistance towards chemo- and radiotherapy. Therefore, inhibitors of specific DNA repair pathways might be advantageous when used in combination with DNA-damaging agents, such as ionizing radiation. This review put particular emphasis on the key DNA repair enzymes: DNA-dependent protein kinase (DNA-PK), ataxia-telangiectasia mutated kinase (ATM) and ATM-Rad3-related kinase (ATR) and their specific inhibitors in the context of radio-sensitization

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biomedical Papers

  • ISSN

    1213-8118

  • e-ISSN

  • Volume of the periodical

    160

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    9

  • Pages from-to

    11-19

  • UT code for WoS article

    000373390800002

  • EID of the result in the Scopus database